Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231884 | 0.81 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6231398 | 0.70 | MGAM (0.44) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20974387 | 0.69 | LMNA (0.39) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6226886 | 0.69 | NPC1 (0.51) | MAPTPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL78691 | 0.68 | CA14 (0.41) | KDM4EMEN1KMT2ABLMHSD17B10 | |
| SCHEMBL6227192 | 0.67 | EGLN1 (0.41) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL2834319 | 0.65 | HDAC3 (0.55) | RECQLALDH1A1BACE1HDAC3HDAC1 | |
| SCHEMBL7594665 | 0.64 | HDAC3 (0.44) | BACE1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL13021076 | 0.63 | CTSL (0.54) | RECQLMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6230849 | 0.63 | CA12 (0.50) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |