Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967151 | 0.76 | SOAT2 (0.45) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL8618922 | 0.76 | SOAT2 (0.58) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL8137246 | 0.73 | FABP3 (0.57) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL8136292 | 0.72 | FABP4 (0.50) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL8879223 | 0.72 | FABP4 (0.48) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL7207609 | 0.72 | SOAT2 (0.45) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL7574177 | 0.71 | SOAT2 (0.49) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL2779847 | 0.71 | SOAT2 (0.62) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL7207662 | 0.70 | FABP4 (0.58) | SOAT2MYCSOAT1MAP2K3FABP4 | |
| SCHEMBL9078229 | 0.70 | SOAT2 (0.48) | SOAT2MYCSOAT1MAP2K3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584333-A2 | Use of acetylcoenzime A inhibitors for treating Alzheimer's disease | Warner-Lambert Company LLC (US) | 2005-10-12 | — | — | EP | claimed |
| WO-1997044314-A1 | N-ACYL SULFAMIC ACID ESTERS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-11-27 | — | — | WO | disclosed |