Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.58 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.58 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229692 | 0.76 | SOAT2 (0.48) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL8962422 | 0.76 | LMNA (0.44) | — | |
| SCHEMBL7080904 | 0.74 | LMNA (0.43) | — | |
| Avasimibe SCHEMBL15876 | 0.73 | SOAT2 (1.00) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL9059564 | 0.73 | SOAT2 (0.46) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL28412857 | 0.71 | SOAT2 (0.68) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL5456119 | 0.70 | SOAT2 (0.67) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL287564 | 0.70 | SOAT2 (0.51) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL5471770 | 0.69 | SOAT2 (0.65) | SOAT2MYCSOAT1MAP2K3FABP3 | |
| SCHEMBL2779847 | 0.69 | SOAT2 (0.62) | SOAT2MYCSOAT1MAP2K3FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747528-A | Chroman derivatives as anti-oxidants | WARNER-LAMBERT COMPANY (US) | 1998-05-05 | — | — | US | disclosed |