Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | FABP3 | P05413 | 2/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962918 | 0.87 | FABP3 (0.38) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL25831162 | 0.84 | FABP3 (0.36) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL20681156 | 0.83 | NLRP3 (0.40) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL8137246 | 0.82 | FABP3 (0.57) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL7207662 | 0.79 | FABP4 (0.58) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL21962203 | 0.79 | GPR35 (0.35) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL8132569 | 0.78 | GABRA1 (0.55) | SOAT2MYCSOAT1MAP2K3GABRA1 | |
| SCHEMBL7484474 | 0.78 | FABP4 (0.67) | FABP4FABP3SOAT2MYCSOAT1 | |
| SCHEMBL23319858 | 0.78 | GLRA1 (0.38) | SOAT2MYCSOAT1MAP2K3LPAR1 | |
| SCHEMBL22774257 | 0.76 | FABP3 (0.39) | FABP4FABP3FABP5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017905-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 2000-01-25 | — | — | US | disclosed |
| US-5807846-A | TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |