Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627187 | 0.86 | GPR119 (0.44) | GPR119 | |
| SCHEMBL2257063 | 0.80 | LRRK2 (0.31) | USP30 | |
| SCHEMBL622973 | 0.79 | GPR119 (0.44) | GPR119USP30 | |
| SCHEMBL627262 | 0.79 | CCNA2 (0.48) | GPR119USP30 | |
| SCHEMBL624921 | 0.78 | PIK3CA (0.49) | GPR119 | |
| SCHEMBL627264 | 0.77 | CKS1B (0.43) | GPR119 | |
| SCHEMBL622971 | 0.77 | ALDH1A1 (0.41) | GPR119USP30 | |
| SCHEMBL627066 | 0.77 | KDM4E (0.46) | GPR119 | |
| SCHEMBL626840 | 0.75 | FYN (0.30) | — | |
| SCHEMBL626842 | 0.75 | FYN (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |