Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627188 | 0.86 | GPR119 (0.40) | GPR119HPGD | |
| SCHEMBL622972 | 0.79 | GPR119 (0.45) | GPR119USP30 | |
| SCHEMBL627884 | 0.79 | CCNA2 (0.50) | GPR119HPGD | |
| SCHEMBL627265 | 0.77 | CKS1B (0.41) | GPR119 | |
| SCHEMBL624922 | 0.77 | PIK3CA (0.42) | GPR119USP30 | |
| SCHEMBL627067 | 0.77 | KDM4E (0.46) | GPR119 | |
| SCHEMBL23291961 | 0.74 | GPR119 (0.42) | GPR119 | |
| SCHEMBL6532070 | 0.74 | GPR119 (0.56) | GPR119USP30 | |
| SCHEMBL628407 | 0.73 | CYP11B2 (0.44) | GPR119 | |
| SCHEMBL25170981 | 0.73 | GPR119 (0.49) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |