Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622972 | 0.86 | GPR119 (0.45) | GPR119 | |
| SCHEMBL624433 | 0.81 | FYN (0.47) | GPR119LIMK2 | |
| SCHEMBL627188 | 0.81 | GPR119 (0.40) | GPR119FAAHLIMK2GLSKDM4E | |
| SCHEMBL627066 | 0.80 | KDM4E (0.46) | GPR119GLSKDM4EPKM | |
| SCHEMBL625330 | 0.79 | PIM1 (0.52) | — | |
| SCHEMBL627262 | 0.76 | CCNA2 (0.48) | GPR119 | |
| SCHEMBL622971 | 0.76 | ALDH1A1 (0.41) | GPR119GLSKDM4EPKM | |
| SCHEMBL627264 | 0.74 | CKS1B (0.43) | GPR119 | |
| SCHEMBL2394158 | 0.73 | KDM4E (0.48) | GPR119LIMK2KDM4EPKM | |
| SCHEMBL1401260 | 0.71 | HPGD (0.53) | GPR119FAAHLIMK2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |