Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231462 | 0.91 | TNF (0.49) | POLBSMN1; SMN2ALDH1A1GAATNF | |
| SCHEMBL6235254 | 0.87 | PTGES (0.49) | POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6236231 | 0.84 | GAA (0.61) | ALDH1A1GAAACHE | |
| SCHEMBL11281250 | 0.81 | POLB (0.47) | POLBKMT2AMEN1SMN1; SMN2HDAC1 | |
| SCHEMBL12180529 | 0.77 | MEN1 (0.58) | POLBKMT2AMEN1SMN1; SMN2HDAC1 | |
| SCHEMBL6230617 | 0.76 | FFAR1 (0.49) | POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19789855 | 0.71 | POLB (0.54) | POLBKMT2AMEN1SMN1; SMN2HDAC1 | |
| SCHEMBL9115691 | 0.71 | TNF (0.58) | POLBKMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3451872 | 0.70 | ACHE (0.55) | POLBSMN1; SMN2ALDH1A1GAATNF | |
| SCHEMBL5275178 | 0.70 | POLB (0.64) | POLBKMT2AMEN1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282397-B1 | USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT | OREAL (FR) | 2005-05-04 | — | — | EP | claimed |
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | L'OREAL (FR) | 2004-02-26 | — | — | US | claimed |
| EP-0858319-B1 | USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION | OREAL (FR) | 2003-07-23 | — | — | EP | claimed |
| US-6153649-A | Use of carboxylic acids having a sulphur function for promoting skin exfoliation or stimulating epidermal regeneration | L'OREAL (FR) | 2000-11-28 | — | — | US | claimed |
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | L'OREAL (FR) | 2004-02-26 | — | — | US | disclosed |
| US-6153649-A | Use of carboxylic acids having a sulphur function for promoting skin exfoliation or stimulating epidermal regeneration | L'OREAL (FR) | 2000-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | TST, STS, MPST | POLB 1334/4885KMT2A 3028/4885MEN1 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.