Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.46 |
| ▸ | RXRG | P48443 | 9/20 | 0.46 |
| ▸ | RXRB | P28702 | 8/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88554 | 0.77 | RXRA (0.50) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL2785505 | 0.74 | RXRA (0.50) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL14471533 | 0.72 | GABRA1 (0.41) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL345598 | 0.71 | GABRA1 (0.48) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL9248524 | 0.70 | GABRA1 (0.42) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL43496 | 0.69 | GABRA1 (0.43) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL64462 | 0.68 | RXRB (0.46) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL93161 | 0.66 | GABRA1 (0.69) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL24625060 | 0.66 | GABRA1 (0.42) | RXRARXRGRXRBGABRA1GABRB2 | |
| SCHEMBL22181552 | 0.66 | GABRA1 (0.48) | RXRARXRGRXRBGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878183-B1 | Adhesive system for dental use | 3M ESPE AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| US-6100314-A | COATING THREE DIFFERENT THIN FILMS ON TEETH, THE ACTIVATOR COMPONENTS IN TWO FILMS REACT TOGETHER INTO CONTACT START THE CURING PROCESS: BY SIMPLE PRESSING, HIGH SPEED; FOR FIXING DENTAL RESTORATIVE MATERIALS TO HARD DENTAL SUBSTANCE | ESPE DENTAL AG (DE) | 2000-08-08 | — | — | US | disclosed |
| EP-0878183-A2 | Adhesive system for dental use | ESPE Dental AG (DE) | 1998-11-18 | — | — | EP | disclosed |