Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.50 |
| ▸ | RXRG | P48443 | 6/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12774495 | 0.79 | ALDH1A1 (0.55) | RXRARXRBRXRGALDH1A1CYP3A4 | |
| SCHEMBL13947613 | 0.77 | CHRNB2 (0.37) | RXRARXRBRXRGALDH1A1CYP3A4 | |
| SCHEMBL6278267 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRPSMD14MAPK1 | |
| SCHEMBL19102061 | 0.76 | POLB (0.44) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL14283536 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRPSMD14MAPK1 | |
| SCHEMBL43496 | 0.76 | GABRA1 (0.43) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL64462 | 0.74 | RXRB (0.46) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL64463 | 0.74 | RXRA (0.40) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL6231234 | 0.74 | RXRA (0.46) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL93161 | 0.72 | GABRA1 (0.69) | RXRARXRBRXRGGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132235-A1 | 2-Component Dental Materials Based On Crosslinked Polymeric Particles Bearing Acylthiourea Groups | IVOCLAR VIVADENT AG (LI) | 2026-05-14 | — | — | US | disclosed |
| US-12510529-B2 | Method for determining authenticity and adulteration of marked petroleum hydrocarbons | SICPA HOLDING SA (CH) | 2025-12-30 | — | — | US | disclosed |
| EP-4591847-A1 | 2-COMPONENT DENTAL MATERIALS BASED ON CROSSLINKED POLYMERIC PARTICLES BEARING ACYLTHIOUREA GROUPS | Ivoclar Vivadent AG (LI) | 2025-07-30 | — | — | EP | disclosed |
| EP-4069806-B1 | METHOD OF MARKING A PETROLEUM HYDROCARBON | SICPA HOLDING SA (CH) | 2025-04-16 | — | — | EP | disclosed |
| EP-3042645-B2 | Dental composites with improved storage stability | IVOCLAR VIVADENT AG (LI) | 2025-03-12 | — | — | EP | disclosed |
| CN-114848503-B | Dental materials based on polymerizable thiourea derivatives | 义获嘉伟瓦登特公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | IVOCLAR VIVADENT AG (LI) | 2025-01-16 | — | — | US | disclosed |
| EP-4488243-A1 | ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY | Ivoclar Vivadent AG (LI) | 2025-01-08 | — | — | EP | disclosed |
| US-20240327736-A1 | METHOD OF MARKING A PETROLEUM HYDROCARBON | SICPA HOLDING SA (CH) | 2024-10-03 | — | — | US | disclosed |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2024-09-10 | — | — | US | disclosed |
| EP-0754675-B1 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 2001-03-21 | — | — | EP | disclosed |
| EP-0709387-B1 | Bicycloaliphatic 2-methylene-1,3-dioxepanes | IVOCLAR AG (LI) | 1999-03-03 | — | — | EP | disclosed |
| EP-0651989-B1 | Calciumhydroxide based multicomponent dental cement | IVOCLAR AG (LI) | 1999-02-24 | — | — | EP | disclosed |
| US-5733968-A | A MONOMERIC ETHYLENICALLY UNSATURATED POLYMERIZABLE COMPOUND HAVING ONE TO FOUR BETA-DICARBONYL GROUPS AND ONE TO FOUR ACRYLIC, ALKACRYLIC OR VINYL AROMATIC GROUPS; COMPLEXING | IVOCLAR AG (DE) | 1998-03-31 | — | — | US | disclosed |
| US-5703249-A | MONOMERS THAT CAN BE POLYMERIZED FOR USE AS COMPOSITES AND DENTAL MATERIALS | IVOCLAR AG (LI) | 1997-12-30 | — | — | US | disclosed |
| US-5698020-A | CONTAINS PHOTOCHROMIC DYE; CAN BE VISUALLY DISTINGUISHED FROM NATURAL TOOTH AFTER IRRADIATING WITH LIGHT | IVOCLAR AG (LI) | 1997-12-16 | — | — | US | disclosed |
| EP-0754675-A2 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 1997-01-22 | — | — | EP | disclosed |
| EP-0744172-A2 | Photochromic dental material | IVOCLAR AG (LI) | 1996-11-27 | — | — | EP | disclosed |
| EP-0709387-A1 | Bicycloaliphatic 2-methylene-1,3-dioxepanes | IVOCLAR AG (LI) | 1996-05-01 | — | — | EP | disclosed |
| EP-0651989-A1 | Calciumhydroxide based multicomponent dental cement | IVOCLAR AG (LI) | 1995-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132235-A1 | 2-Component Dental Materials Based On Crosslinked Polymeric Particles Bearing Acylthiourea Groups | HBG1, TCP1, GSTM1 | RXRA 1714/4885RXRB 2216/4885RXRG 2305/4885 |
| US-12510529-B2 | Method for determining authenticity and adulteration of marked petroleum hydrocarbons | CYP4A11, CYP11B1, CYP11A1 | RXRA 60/4885RXRB 49/4885RXRG 101/4885 |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | TAS2R10, PAM, HBG1 | RXRA 1513/4885RXRB 1903/4885RXRG 1969/4885 |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | HAO2, HAO1, CDH1 | RXRA 173/4885RXRB 406/4885RXRG 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.