Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 11/20 | 0.46 |
| ▸ | RXRA | P19793 | 10/20 | 0.46 |
| ▸ | RXRG | P48443 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785505 | 0.74 | RXRA (0.50) | RXRBRXRARXRGHPGDTSHR | |
| SCHEMBL28240841 | 0.69 | RXRA (0.46) | RXRBRXRARXRGHPGDTSHR | |
| SCHEMBL43496 | 0.69 | GABRA1 (0.43) | RXRBRXRARXRGHPGDRAB9A | |
| SCHEMBL6231234 | 0.68 | RXRA (0.46) | RXRBRXRARXRGTSHRHDAC8 | |
| SCHEMBL64463 | 0.68 | RXRA (0.40) | RXRBRXRARXRGTSHRHDAC8 | |
| SCHEMBL27857311 | 0.67 | ACHE (0.46) | RXRBRXRARXRGRAB9AHDAC8 | |
| SCHEMBL11473066 | 0.67 | RXRA (0.62) | RXRBRXRARXRGHPGDTSHR | |
| SCHEMBL11103938 | 0.66 | RXRB (0.45) | RXRBRXRARXRGRAB9AGABRA1 | |
| SCHEMBL29220490 | 0.66 | LMNA (0.52) | RXRBRXRARXRGHPGDTSHR | |
| SCHEMBL88554 | 0.66 | RXRA (0.50) | RXRBRXRARXRGHDAC8GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121658-A1 | SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-06-13 | — | — | WO | disclosed |
| US-11998417-B2 | Process for producing a surface-modified dental article | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-06-04 | — | — | US | disclosed |
| US-11992539-B2 | Curable dental compositions and uses thereof | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-05-28 | — | — | US | disclosed |
| EP-4362881-A1 | DENTAL CEMENT COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M Innovative Properties Company (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2024057144-A1 | DENTAL PRODUCT WITH REDUCED EXTRUSION FORCES | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20230404861-A1 | CURABLE DENTAL COMPOSITIONS AND USES THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-12-21 | — | — | US | disclosed |
| EP-4251117-A1 | CURABLE DENTAL COMPOSITIONS AND USES THEREOF | 3M Innovative Properties Company (US) | 2023-10-04 | — | — | EP | disclosed |
| US-20230225829-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-07-20 | — | — | US | disclosed |
| EP-4175584-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | 3M Innovative Properties Company (US) | 2023-05-10 | — | — | EP | disclosed |
| WO-2023275637-A1 | DENTAL CEMENT COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-01-05 | — | — | WO | disclosed |
| US-20040110864-A1 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-1242493-B1 | RADICALLY CURABLE URETHANE PREPOLYMERS AND THEIR USE IN DENTAL MATERIALS | ESPE DENTAL AG (DE) | 2003-10-08 | — | — | EP | disclosed |
| EP-1222220-B1 | FILLER FOR PLASTIC FORMULATIONS BASED ON POLYURETHANE | 3M ESPE AG (DE) | 2003-08-13 | — | — | EP | disclosed |
| EP-0717977-B1 | Fluoride releasing dental composite material | 3M ESPE AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-20030008967-A1 | Radically curable urethane prepolymers and their use in dental materials | 3M INNOVATIVE PROPERTIES COMPANY | 2003-01-09 | — | — | US | disclosed |
| US-5968998-A | ADDITIONALLY CONTAINING SPECIFIED UNSATURATED ARYL COMPOUND TO LENGTHEN SETTING TIME | ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) | 1999-10-19 | — | — | US | disclosed |
| US-5824720-A | DI OR MULTI(METH)ACRYLATES, INITIATORS, ACTIVATORS, FILLERS AND FLUORIDE COMPLEXES FOR DENTAL FILLING | THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5583164-A | FREE RADICAL POLYMERIZATION; DELAY CURING | ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) | 1996-12-10 | — | — | US | disclosed |
| EP-0717977-A2 | Fluoride releasing dental composite material | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0374824-B1 | DENTAL COMPOSITIONS CONTAINING BIFUNCTIONAL ACRYLIC OR METHACRYLIC ACID ESTERS | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1993-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230404861-A1 | CURABLE DENTAL COMPOSITIONS AND USES THEREOF | H1-0, COL1A1, HAX1 | RXRB 317/4885RXRA 191/4885RXRG 206/4885 |
| US-11992539-B2 | Curable dental compositions and uses thereof | H1-0, COL1A1, HAX1 | RXRB 317/4885RXRA 191/4885RXRG 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.