Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 7/20 | 0.41 |
| ▸ | RXRB | P28702 | 7/20 | 0.41 |
| ▸ | RXRG | P48443 | 7/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990578 | 0.81 | CYP2D6 (0.44) | RXRARXRBMAPTALDH1A1KDM4E | |
| SCHEMBL44011 | 0.79 | LMNA (0.43) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL2785505 | 0.76 | RXRA (0.50) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL20599272 | 0.73 | EGFR (0.36) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL24885665 | 0.72 | ALDH1A1 (0.64) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL43166 | 0.71 | MAPT (0.38) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL7931679 | 0.71 | GABRA1 (0.39) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL88554 | 0.71 | RXRA (0.50) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL14003144 | 0.71 | TSPO (0.33) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL14372107 | 0.70 | GABRA1 (0.52) | GABRA1GABRB2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144714-A1 | KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL | MITSUI CHEMICALS, INC. (JP) | 2026-05-28 | — | — | US | disclosed |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | KURARAY NORITAKE DENTAL INC. (JP) | 2026-05-12 | — | — | US | disclosed |
| US-20260124121-A1 | POLYMERIZABLE DENTAL COMPOSITION | TROETSCHLER TOBIAS (DE) | 2026-05-07 | — | — | US | disclosed |
| EP-4736833-A1 | POLYMERIZABLE DENTAL COMPOSITION | DENTSPLY SIRONA Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-3861977-B1 | (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2026-05-06 | — | — | EP | disclosed |
| EP-4725470-A1 | CURABLE DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-12564543-B2 | Dental composition | KURARAY NORITAKE DENTAL INC. (JP) | 2026-03-03 | — | — | US | disclosed |
| US-12527725-B2 | Solvent-free dental adhesive composition | KURARAY NORITAKE DENTAL INC. (JP) | 2026-01-20 | — | — | US | disclosed |
| US-12478562-B2 | Dental restoration material composition | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-25 | — | — | US | disclosed |
| EP-4649938-A1 | DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2025-11-19 | — | — | EP | disclosed |
| EP-0948955-A1 | POLYMERIZABLE DENTAL COMPOSITION | KURARAY CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0878183-A2 | Adhesive system for dental use | ESPE Dental AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0040232-B2 | USE OF SILICIC ACID PELLETS AS FILLERS FOR DENTAL MATERIALS | ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0017151-B1 | COLD CURING MATERIALS FOR DENTAL PURPOSES WITH POLYMERISATION-ACTIVE SULFONES | BAYER AG (DE) | 1984-02-15 | — | — | EP | disclosed |
| EP-0040232-B1 | USE OF SILICIC ACID PELLETS AS FILLERS FOR DENTAL MATERIALS | ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) | 1983-11-02 | — | — | EP | disclosed |
| US-4389497-A | Use of agglomerates of silicic acid as fillers in dental materials | ESPE FABRIK PARMAZEUTISCHER PRAPARATE GMBH (DE) | 1983-06-21 | — | — | US | disclosed |
| EP-0040232-A1 | USE OF SILICIC ACID PELLETS AS FILLERS FOR DENTAL MATERIALS. | ESPE PHARM PRAEP (DE) | 1981-11-25 | — | — | EP | disclosed |
| WO-1981001366-A1 | USE OF SILICIC ACID PELLETS AS EXIPIENTS FOR DENTAL MASS MATERIAL | ESPE PHARM PRAEP (DE) | 1981-05-28 | — | — | WO | disclosed |
| EP-0017151-A2 | Cold curing materials for dental purposes with polymerisation-active sulfones | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
| US-4131729-A | Dental compositions comprising acrylic esters of tricyclo [5.2.1.02,6 ] decane polymers | ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527725-B2 | Solvent-free dental adhesive composition | CDH1, ITGA1, ITGB8 | GABRA1 2463/4885GABRB2 2392/4885RXRA 733/4885 |
| US-20260144714-A1 | KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL | CAD, KIT, ILK | GABRA1 4011/4885GABRB2 4600/4885RXRA 1532/4885 |
| US-12564543-B2 | Dental composition | CAD, ARCN1, MAT1A | GABRA1 1271/4885GABRB2 2384/4885RXRA 2241/4885 |
| US-12478562-B2 | Dental restoration material composition | CAD, MAT2B, RER1 | GABRA1 842/4885GABRB2 1582/4885RXRA 212/4885 |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | MSL1, ITGA1, ITGAL | GABRA1 4487/4885GABRB2 4777/4885RXRA 992/4885 |
| US-20260124121-A1 | POLYMERIZABLE DENTAL COMPOSITION | F12, RAD51, PFN1 | GABRA1 2518/4885GABRB2 3449/4885RXRA 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.