⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009306 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL28119517 | 0.82 | MEN1 (0.33) | — | |
| SCHEMBL11562139 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL28054486 | 0.75 | OPRM1 (0.30) | — | |
| SCHEMBL3219070 | 0.75 | MEN1 (0.33) | — | |
| SCHEMBL28680577 | 0.74 | LMNA (0.32) | — | |
| SCHEMBL17024087 | 0.73 | OPRM1 (0.33) | — | |
| SCHEMBL28497539 | 0.72 | L3MBTL1 (0.33) | — | |
| SCHEMBL10479149 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL17475610 | 0.72 | SIGMAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852488-B2 | TOPICAL COMPOSITION CONTAINING A SILICONE-GRAFTED POLYMER AND AN AMINE SILICONE AND/OR A SILICONE GUM OR RESIN | OREAL (FR) | 2005-04-20 | — | — | EP | claimed |
| EP-0852488-B1 | TOPICAL COMPOSITION CONTAINING A SILICONE-GRAFTED POLYMER AND AN AMINE SILICONE AND/OR A SILICONE GUM OR RESIN | OREAL (FR) | 2001-08-16 | — | — | EP | claimed |
| EP-0852488-A1 | TOPICAL COMPOSITION CONTAINING A SILICONE-GRAFTED POLYMER AND AN AMINE SILICONE AND/OR A SILICONE GUM OR RESIN | L'OREAL (FR) | 1998-07-15 | — | — | EP | claimed |
| WO-1997012594-A1 | TOPICAL COMPOSITION CONTAINING A SILICONE-GRAFTED POLYMER AND AN AMINE SILICONE AND/OR A SILICONE GUM OR RESIN | L'OREAL (FR) | 1997-04-10 | — | — | WO | claimed |