Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | HPGD | P15428 | 10/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 11/20 | 0.34 |
| ▸ | RAB9A | P51151 | 11/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.32 |
| ▸ | TP53 | P04637 | 9/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675235 | 0.71 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL3128277 | 0.68 | NPC1 (0.60) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL8991921 | 0.68 | RAB9A (0.53) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL824391 | 0.68 | NPC1 (0.60) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL12776968 | 0.67 | MAPT (0.44) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL8327904 | 0.66 | RAB9A (0.44) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL11362017 | 0.65 | NPC1 (0.45) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL1515611 | 0.65 | RAB9A (0.42) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL12861184 | 0.63 | PTGS2 (0.47) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL15798462 | 0.63 | RAB9A (0.43) | KDM4EALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |