SCHEMBL6232386

SCHEMBL6232386

C=CCOc1cc(C(C)C)ccc1C

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 12/20 0.58
BCHE P06276 9/20 0.52
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
LMNA P02545 2/20 0.49
ALDH1A1 P00352 1/20 0.49
TRPA1 O75762 1/20 0.42
PTGS1 P23219 1/20 0.42
CACNA1C Q13936 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10152999 0.82 KDM4E (0.54) ACHEHTTSMN1; SMN2L3MBTL1LMNA
SCHEMBL20206848 0.82 ACHE (0.41) ACHEBCHEHTTSMN1; SMN2L3MBTL1
SCHEMBL26521879 0.80 ACHE (0.39) ACHEHTTLMNAALDH1A1
SCHEMBL29654960 0.79 ACHE (0.63) ACHEBCHEHTTSMN1; SMN2L3MBTL1
SCHEMBL356804 0.79 ACHE (0.63) ACHEBCHEHTTSMN1; SMN2L3MBTL1
SCHEMBL7816047 0.79 HPGD (0.51) HTTSMN1; SMN2LMNAALDH1A1
SCHEMBL806191 0.79 ACHE (0.39) ACHEBCHEHTTLMNAALDH1A1
SCHEMBL2739323 0.79 ADRA2A (0.43) ACHEHTTLMNAALDH1A1
SCHEMBL11135055 0.78 ACHE (0.53) ACHEBCHEHTTSMN1; SMN2L3MBTL1
SCHEMBL19121433 0.77 ACHE (0.60) ACHEBCHEHTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115975202-A Siloxane-modified fluorine-containing antibacterial polymethyl siloxane with antibacterial hydrophobic function and preparation method and application thereof 苏州东杏新材料科技有限公司 2023-04-18 CN claimed
CN-115975202-A Siloxane-modified fluorine-containing antibacterial polymethyl siloxane with antibacterial hydrophobic function and preparation method and application thereof 苏州东杏新材料科技有限公司 2023-04-18 CN disclosed
US-20220031908-A1 Injectable Therapeutic Biocompatible Co-Polymers and Methods of Making and Using Same MOREHOUSE COLLEGE 2022-02-03 US disclosed
US-20180147318-A1 Injectable Therapeutic Biocompatible Co-Polymers and Methods of Making and Using Same MOREHOUSE COLLEGE 2018-05-31 US disclosed
US-20180147318-A1 Injectable Therapeutic Biocompatible Co-Polymers and Methods of Making and Using Same MOREHOUSE COLLEGE 2018-05-31 US disclosed
WO-2016187327-A1 INJECTABLE THERAPEUTIC BIOCOMPATIBLE CO-POLYMERS AND METHODS OF MAKING AND USING SAME MENDENHALL JUANA (US) 2016-11-24 WO disclosed
EP-1053744-B1 Substituted phenols as fragrance, flavor and antimicrobial compounds TAKASAGO PERFUMERY CO LTD (JP) 2005-04-27 EP disclosed
EP-1053744-A2 Substituted phenols as fragrance, flavor and antimicrobial compounds Takasago International Corporation (JP) 2000-11-22 EP disclosed
US-6110888-A PHENOL SUBSTITUTED WITH ONE OF: PROPYL OR PROPENYL; ONE OF: HYDROGEN OR ALKYL; AND ONE TO THREE C3-C5 ALKYL GROUPS; FRAGRANCE AND ANTIMICROBIAL PROPERTIES; USE SUCH AS IN MOUTHWASHES TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180147318-A1 Injectable Therapeutic Biocompatible Co-Polymers and Methods of Making and Using Same CD44, COL2A1, MMP1 ACHE 1432/4885BCHE 1606/4885HTT 392/4885
US-20220031908-A1 Injectable Therapeutic Biocompatible Co-Polymers and Methods of Making and Using Same CD44, COL2A1, MMP1 ACHE 1543/4885BCHE 1588/4885HTT 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.