Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707646 | 0.85 | TSHR (0.42) | TSHRTHRB | |
| SCHEMBL10876486 | 0.82 | THRB (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL2349030 | 0.76 | TSHR (0.57) | TSHRTHRBALDH1A1 | |
| 1,1-Dichloroethene SCHEMBL1697653 | 0.74 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL7619457 | 0.74 | TSHR (0.40) | TSHR | |
| Acrylonitrile SCHEMBL9562514 | 0.73 | TSHR (0.75) | TSHRTHRBALDH1A1 | |
| Acrylonitrile SCHEMBL6658905 | 0.72 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL371302 | 0.71 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| Water SCHEMBL7715061 | 0.71 | TSHR (0.70) | TSHRTHRBALDH1A1 | |
| SCHEMBL3447191 | 0.71 | MEN1 (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506239-A2 | SURFACE GRAFT MODIFIED RESINS AND FORMATION THEREOF | Phenomenex, Inc. (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003064478-A2 | SURFACE GRAFT MODIFIED RESINS AND FORMATION THEREOF | PHENOMENEX, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-0076404-B1 | METHOD FOR RECOVERY OF GALLIUM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-01-29 | — | — | EP | disclosed |
| US-4468374-A | AMIDOOXIME CHELATE RESIN | SIMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-28 | — | — | US | disclosed |
| EP-0076404-A1 | Method for recovery of gallium | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-04-13 | — | — | EP | disclosed |