1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL1697653

C=C(C)C(=O)OC(C=CC#N)OC(=O)C(=C)C.C=C(Cl)Cl

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232828 0.74 TSHR (0.47) ALDH1A1TSHR
SCHEMBL6142595 0.72 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL6142594 0.72 ALDH1A1 (0.41) ALDH1A1TSHR
Methacrylic Acid SCHEMBL5276743 0.70
SCHEMBL28053784 0.69 ALDH1A1 (0.65) ALDH1A1TSHR
SCHEMBL15364016 0.69 ALDH1A1 (0.41) ALDH1A1TSHR
1,1-Dichloroethene SCHEMBL667752 0.68 ALDH1A1 (0.58) ALDH1A1TSHR
Acrylonitrile SCHEMBL8587637 0.68 TSHR (0.42) ALDH1A1TSHR
Acetone SCHEMBL17668914 0.67 ALDH1A1 (0.39) ALDH1A1TSHR
Acrylonitrile SCHEMBL10732006 0.67 TSHR (0.41) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4362908-A1 COSMETIC COMPOSITION CONTAINING A RHEOLOGICAL-MODIFYING AND STABILIZING POLYMER BLEND L'OREAL (FR) 2024-05-08 EP disclosed
US-11865197-B2 Cosmetic compositions having stabilized retinol L'OREAL (FR) 2024-01-09 US disclosed
EP-4171486-A1 COSMETIC COMPOSITION PROVIDING UNIQUE SENSORIAL SENSATIONS L'OREAL (FR) 2023-05-03 EP disclosed
EP-4171487-A1 COSMETIC COMPOSITION FOR IMPROVED PENETRATION L'OREAL (FR) 2023-05-03 EP disclosed
EP-4171476-A1 COSMETIC COMPOSITIONS HAVING STABILIZED RETINOL L'OREAL (FR) 2023-05-03 EP disclosed
CN-115996697-A Cosmetic composition with improved penetration 莱雅公司 2023-04-21 CN disclosed
US-11554086-B2 Cosmetic composition comprising glycolic acid and methods of use L'OREAL (FR) 2023-01-17 US disclosed
WO-2023278511-A1 COSMETIC COMPOSITION CONTAINING A RHEOLOGICAL-MODIFYING AND STABILIZING POLYMER BLEND L'OREAL (FR) 2023-01-05 WO disclosed
US-20220409514-A1 COSMETIC COMPOSITION CONTAINING A RHEOLOGICAL-MODIFYING AND STABILIZING POLYMER BLEND L'OREAL (FR) 2022-12-29 US disclosed
US-11534381-B2 Cosmetic composition for improved penetration L'OREAL (FR) 2022-12-27 US disclosed
US-20130315650-A1 COSMETIC COMPOSITION FOR FACE AND THE AREA AROUND THE EYES L'OREAL (FR) 2013-11-28 US disclosed
EP-2640341-A1 COSMETIC COMPOSITION FOR CARING FOR AND / OR MAKE UP FOR THE FACE AND EYES L'Oréal (FR) 2013-09-25 EP disclosed
US-20130164235-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ORGANOPOLYSILOXANE ELASTOMER AND AT LEAST ONE TACKIFYING RESIN L'OREAL (FR) 2013-06-27 US disclosed
EP-2588076-A2 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ORGANOPOLYSILOXANE ELASTOMER AND AT LEAST ONE TACKIFYING RESIN L'Oréal (FR) 2013-05-08 EP disclosed
WO-2012066097-A1 COSMETIC COMPOSITION FOR CARING FOR AND / OR MAKE UP FOR THE FACE AND EYES L'OREAL (FR) 2012-05-24 WO disclosed
WO-2012001172-A2 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ORGANOPOLYSILOXANE ELASTOMER AND AT LEAST ONE TACKIFYING RESIN L'OREAL (FR) 2012-01-05 WO disclosed
US-20110206748-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ACTIVE AGENT AND PARTICLES CONTAINING AT LEAST ONE COLORED INORGANIC PIGMENT IN A MATRIX, AND SKINCARE USE THEREOF L'OREAL S.A (FR) 2011-08-25 US disclosed
US-20100197805-A1 COMPOSITION FOR IMPROVING THE SURFACE APPEARANCE OF THE SKIN L'OREAL (FR) 2010-08-05 US disclosed
US-20100047298-A1 PROCESS FOR TREATING THE SKIN BY APPLYING SILICONE COMPOUNDS L'OREAL (FR) 2010-02-25 US disclosed
US-20070065382-A1 Cosmetic composition comprising at least one active agent and particles containing at least one colored inorganic pigment in a matrix, and skincare use thereof L'OREAL S.A. (FR) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220409514-A1 COSMETIC COMPOSITION CONTAINING A RHEOLOGICAL-MODIFYING AND STABILIZING POLYMER BLEND ACMSD, ALKBH5, MMAB ALDH1A1 1308/4885TSHR 3961/4885
US-11865197-B2 Cosmetic compositions having stabilized retinol RBP4, RBP1, RARG ALDH1A1 188/4885TSHR 1473/4885
US-20100197805-A1 COMPOSITION FOR IMPROVING THE SURFACE APPEARANCE OF THE SKIN CUTA, PSPH, COL14A1 ALDH1A1 3419/4885TSHR 3449/4885
US-11534381-B2 Cosmetic composition for improved penetration UGCG, DSG1, DDOST ALDH1A1 1467/4885TSHR 4819/4885
US-11554086-B2 Cosmetic composition comprising glycolic acid and methods of use CUTA, UGCG, DGKI ALDH1A1 2910/4885TSHR 1494/4885
US-20100047298-A1 PROCESS FOR TREATING THE SKIN BY APPLYING SILICONE COMPOUNDS CUTA, PIEZO1, NISCH ALDH1A1 2557/4885TSHR 3774/4885
US-20130164235-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ORGANOPOLYSILOXANE ELASTOMER AND AT LEAST ONE TACKIFYING RESIN KRT18, COL1A1, COL2A1 ALDH1A1 487/4885TSHR 2899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.