Styrene

Styrene

SCHEMBL6233548

C=C(CCO)C(=O)[O-].C=Cc1ccccc1.O=S(=O)(O)C=Cc1ccccc1.[K+]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.33
YAP1 P46937 1/20 0.33
TEAD4 Q15561 1/20 0.33
PPARG P37231 3/20 0.33
LMNA P02545 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PAM P19021 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL18818304 0.87 ALDH1A1 (0.47) TDP1TSHRALDH1A1HTTLMNA
Styrene SCHEMBL7849011 0.86 GAA (0.38) GAATDP1HTTPPARGLMNA
Styrene SCHEMBL7940876 0.85 HTT (0.38) GAATDP1TSHRALDH1A1HTT
Styrene SCHEMBL7854979 0.81 HTT (0.36) GAAALDH1A1HTTPPARG
Styrene SCHEMBL210091 0.81 TSHR (0.54) GAATDP1TSHRALDH1A1HTT
SCHEMBL7940863 0.80 GAA (0.40) GAATDP1HTTPPARGLMNA
Styrene SCHEMBL16267533 0.79 TSHR (0.52) GAATDP1TSHRALDH1A1HTT
Styrene SCHEMBL1979409 0.79 TSHR (0.52) GAATDP1TSHRALDH1A1HTT
Styrene SCHEMBL29892483 0.79 TSHR (0.52) GAATDP1TSHRALDH1A1HTT
Acrylic Acid SCHEMBL16564293 0.78 HTT (0.42) GAATDP1ALDH1A1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10816829-B2 Optical film and method for producing optical film Konica Minolta, Inc. (JP) 2020-10-27 US disclosed
US-10281619-B2 Laminated film and method of producing the same Konica Minolta, Inc. (JP) 2019-05-07 US disclosed
US-20170307910-A1 OPTICAL FILM AND METHOD FOR PRODUCING OPTICAL FILM Konica Minolta, Inc. (JP) 2017-10-26 US disclosed
EP-2687878-B1 HEAT-RAY REFLECTING FILM, METHOD FOR PRODUCING SAME, AND HEAT-RAY REFLECTING BODY KONICA MINOLTA INC (JP) 2017-08-16 EP disclosed
US-20160370507-A1 LAMINATED FILM AND METHOD OF PRODUCING THE SAME Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160271910-A1 HEAT RAY SHIELDING LAMINATED GLASS AND MANUFACTURING METHOD FOR HEAT RAY SHIELDING LAMINATED GLASS Konica Minolta, Inc. (JP) 2016-09-22 US disclosed
US-9366788-B2 Heat radiation reflective film and method for producing the same, and heat radiation reflector Konica Minolta, Inc. (JP) 2016-06-14 US disclosed
EP-2977362-A1 HEAT RAY SHIELDING LAMINATED GLASS AND MANUFACTURING METHOD FOR HEAT RAY SHIELDING LAMINATED GLASS Konica Minolta, Inc. (JP) 2016-01-27 EP disclosed
EP-2808710-A1 OPTICAL FILM Konica Minolta Advanced Layers, Inc. (JP) 2014-12-03 EP disclosed
US-20140333996-A1 OPTICAL FILM Konica Minolta, Inc. (JP) 2014-11-13 US disclosed
US-20140192413-A1 OPTICAL REFLECTIVE FILM KONICA MINOLTA , INC. (JP) 2014-07-10 US disclosed
EP-2725395-A1 OPTICAL REFLECTIVE FILM Konica Minolta, Inc. (JP) 2014-04-30 EP disclosed
EP-2687878-A1 HEAT-RAY REFLECTING FILM, METHOD FOR PRODUCING SAME, AND HEAT-RAY REFLECTING BODY Konica Minolta, Inc. (JP) 2014-01-22 EP disclosed
US-20140002895-A1 HEAT RADIATION REFLECTIVE FILM AND METHOD FOR PRODUCING THE SAME, AND HEAT RADIATION REFLECTOR KONICA MINOLTA , INC. (JP) 2014-01-02 US disclosed
US-6949138-B2 Pigment dispersion liquid, manufacturing process thereof, pigment ink for ink jetting, and ink jet image recording method employing the same KONICA CORPORATION (JP) 2005-09-27 US disclosed
EP-1215251-B1 Pigment dispersion liquid for ink jetting KONISHIROKU PHOTO IND (JP) 2005-06-15 EP disclosed
US-20020112644-A1 Pigment dispersion liquid, manufacturing process thereof, pigment ink for ink jetting, and ink jet image recording method employing the same KONICA CORPORATION (JP) 2002-08-22 US disclosed
EP-1215251-A1 Pigment dispersion liquid for ink jetting Konica Corporation (JP) 2002-06-19 EP disclosed