Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234719 | 0.84 | DHODH (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6685562 | 0.80 | ALDH1A1 (0.57) | LMNAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1647131 | 0.77 | AR (0.44) | LMNAALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL18600867 | 0.77 | AR (0.44) | LMNAALDH1A1CYP2C9CYP2C19RAB9A | |
| SCHEMBL1508495 | 0.76 | VCAM1 (0.57) | LMNAVCAM1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4319388 | 0.76 | ALDH1A1 (0.54) | LMNAVCAM1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4643645 | 0.75 | CTSV (0.57) | LMNAVCAM1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2362378 | 0.75 | MAOA (0.58) | LMNAALDH1A1CYP2C9CYP2C19RAB9A | |
| SCHEMBL11699501 | 0.75 | LMNA (0.71) | LMNAVCAM1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4909005 | 0.75 | SMN1; SMN2 (0.57) | ALDH1A1RAB9AMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |