Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231706 | 0.88 | LMNA (0.53) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6231703 | 0.88 | LMNA (0.53) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6233776 | 0.84 | CD274 (0.45) | KMT2AMEN1TDP1 | |
| SCHEMBL6230535 | 0.82 | CD274 (0.46) | KMT2AMEN1TDP1BCHECTSA | |
| SCHEMBL6233814 | 0.82 | FFAR4 (0.45) | KMT2AMEN1TDP1ALDH1A1BCHE | |
| SCHEMBL6232051 | 0.81 | MEN1 (0.51) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6230153 | 0.81 | MEN1 (0.51) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6237847 | 0.81 | BCHE (0.54) | KMT2AMEN1MAPK1NPSR1BCHE | |
| SCHEMBL6237852 | 0.81 | BCHE (0.54) | KMT2AMEN1MAPK1NPSR1BCHE | |
| SCHEMBL6233689 | 0.80 | CD274 (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |