Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271807 | 0.86 | EGFR (0.39) | MKNK1EGFRERBB2PIP4K2APIP4K2C | |
| SCHEMBL6233688 | 0.85 | EGFR (0.36) | ALDH1A1EGFRERBB2PIP4K2APIP4K2C | |
| SCHEMBL6269171 | 0.83 | EGFR (0.41) | ALDH1A1TSHREGFRERBB2RORC | |
| SCHEMBL6239978 | 0.82 | EGFR (0.47) | MKNK1EGFRERBB2FLT1 | |
| SCHEMBL6235814 | 0.73 | EGFR (0.49) | ALDH1A1TSHREGFRPIP4K2APIP4K2C | |
| SCHEMBL6271801 | 0.72 | EGFR (0.52) | EGFRERBB2 | |
| SCHEMBL6271804 | 0.72 | EGFR (0.52) | EGFRERBB2 | |
| SCHEMBL6236350 | 0.71 | FLT1 (0.49) | EGFRERBB2FLT1 | |
| SCHEMBL6236088 | 0.70 | PIP4K2A (0.40) | MKNK1EGFRERBB2PIP4K2A | |
| SCHEMBL6269168 | 0.70 | EGFR (0.54) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |