Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390732 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| SCHEMBL6387441 | 0.93 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| SCHEMBL6241015 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| Hydrochloric Acid SCHEMBL6387557 | 0.84 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| SCHEMBL26515833 | 0.82 | RAB9A (0.45) | ALDH1A1ALOX15L3MBTL1TSHRSIGMAR1 | |
| SCHEMBL10955815 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| SCHEMBL11787777 | 0.80 | MAPT (0.49) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| SCHEMBL6239446 | 0.80 | S100B (0.45) | ALDH1A1CYP3A4TDP1TSHRSIGMAR1 | |
| SCHEMBL20764387 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1MAPK1TP53 | |
| SCHEMBL27504680 | 0.79 | EPHX1 (0.43) | SIGMAR1MAPTEPHX1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050132507-A1 | Tertiary p-phenylenediamines, dyes compositions, and dyeing processes | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | claimed |
| CN-1660773-A | Tertiary p-phenylenediamines, dyes compositions comprising thereof, and dyeing processes using the same | OREAL (FR) | 2005-08-31 | — | — | CN | disclosed |
| US-20050132507-A1 | Tertiary p-phenylenediamines, dyes compositions, and dyeing processes | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| EP-1535899-A1 | Dyeing composition comprising at least one tertiary particular p-phenylenediamine, colouring method using same | L'OREAL (FR) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050132507-A1 | Tertiary p-phenylenediamines, dyes compositions, and dyeing processes | KRT18, CDC73, DSP | ALDH1A1 1367/4885CYP3A4 1356/4885TDP1 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.