Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 5/20 | 0.37 |
| ▸ | NOS2 | P35228 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484916 | 0.83 | S100B (0.53) | S100BALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL27603360 | 0.83 | NOS1 (0.33) | NOS1NOS2SYKSIGMAR1MAPT | |
| SCHEMBL29740664 | 0.81 | S100B (0.60) | S100BNOS1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10955324 | 0.81 | S100B (0.60) | S100BNOS1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5500237 | 0.80 | S100B (0.49) | S100BNOS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL6234580 | 0.80 | ALDH1A1 (0.41) | NOS1NOS2ALDH1A1CYP3A4TSHR | |
| SCHEMBL5502903 | 0.78 | S100B (0.50) | S100BNOS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL6390732 | 0.78 | ALDH1A1 (0.42) | NOS1NOS2ALDH1A1CYP3A4TSHR | |
| SCHEMBL16003239 | 0.76 | S100B (0.55) | S100BNOS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL26515833 | 0.76 | RAB9A (0.45) | ALDH1A1TSHRSYKSIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050132507-A1 | Tertiary p-phenylenediamines, dyes compositions, and dyeing processes | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| EP-1535899-A1 | Dyeing composition comprising at least one tertiary particular p-phenylenediamine, colouring method using same | L'OREAL (FR) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050132507-A1 | Tertiary p-phenylenediamines, dyes compositions, and dyeing processes | KRT18, CDC73, DSP | S100B 135/4885NOS1 2637/4885NOS2 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.