SCHEMBL9560533

SCHEMBL9560533

CCCc1c(-c2ccc(O)c(Br)c2)ccc(O)c1Br

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
ALOX15 P16050 2/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
ESR1 P03372 8/20 0.35
ESR2 Q92731 6/20 0.34
MCL1 Q07820 1/20 0.34
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLH Q9Y253 1/20 0.33
HSD17B1 P14061 1/20 0.33
USP7 Q93009 1/20 0.32
ALOX12 P18054 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6235059 0.75 CNR1 (0.42) ALOX5CNR1CNR2MCL1
SCHEMBL8057962 0.70 ESR2 (0.45) ALOX5CNR1CNR2GABRA1GABRB2
SCHEMBL3231646 0.70 ALOX5 (0.42) ALOX5CNR1CNR2GABRA1GABRB2
SCHEMBL18371594 0.69 HPGD (0.39) CNR1CNR2ALOX15ESR1ESR2
SCHEMBL9560140 0.69 CRHBP (0.36) CNR1CNR2ALOX15GABRA1GABRB2
SCHEMBL30268624 0.69 ALOX15 (0.62) ALOX5ALOX15ESR1ESR2MAPT
SCHEMBL5028631 0.69 ALOX15 (0.62) ALOX5ALOX15ESR1ESR2MAPT
SCHEMBL28871536 0.69 CNR1 (0.39) ALOX5CNR1CNR2ALOX15ESR1
SCHEMBL10908327 0.69 ALDH1A1 (0.38) CNR1CNR2GABRA1GABRB2MCL1
SCHEMBL3699399 0.69 CNR1 (0.64) ALOX5CNR1CNR2ALOX15GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277804-B1 POLYCARBONATE FILMS EFFECTIVE AS OPTICAL PHASE RETARDERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-29 EP disclosed
US-5061042-A Phase retarder and liquid crystal display using the same SUMITOMO CHEMICAL CO., LTD. (JP) 1991-10-29 US disclosed