Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183883 | 0.72 | LMNA (0.33) | HSD11B1 | |
| Bicarbonate SCHEMBL7732897 | 0.68 | HSD11B1 (0.36) | HSD11B1EPHX1EPHX2 | |
| Bicarbonate SCHEMBL7739291 | 0.68 | HSD11B1 (0.36) | HSD11B1EPHX1EPHX2 | |
| SCHEMBL294644 | 0.67 | EPHX1 (0.35) | EPHX1EPHX2 | |
| SCHEMBL15922703 | 0.67 | EPHX1 (0.35) | EPHX1EPHX2 | |
| SCHEMBL15922722 | 0.64 | GRIN2D (0.36) | EPHX1EPHX2 | |
| SCHEMBL29200801 | 0.62 | ALDH1A1 (0.44) | — | |
| SCHEMBL28262550 | 0.62 | GRIN2D (0.36) | — | |
| SCHEMBL2191558 | 0.59 | GRIN2D (0.36) | EPHX2 | |
| SCHEMBL29012477 | 0.59 | THRB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556019-A2 | COMBINATION THERAPY USING 1-AMINOCYCLOHEXANE DERIVATIVES AND ACETYLCHOLINESTERASE INHIBITORS | Merz Pharma GmbH & Co. KGaA (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-1523309-A2 | NMDA RECEPTOR ANTAGONISTS AND THEIR USE IN INHIBITING ABNORMAL HYPERPHOSPHORYLATION OF MICROTUBULE ASSOCIATED PROTEIN TAU | Iqbal, Khalid (US) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004037234-A2 | COMBINATION THERAPY USING 1-AMINOCYCLOHEXANE DERIVATIVES AND ACETYLCHOLINESTERASE INHIBITORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004009062-A2 | NMDA RECEPTOR ANTAGONISTS AND THEIR USE IN INHIBITING ABNORMAL HYPERPHOSPHORYLATION OF MICROTUBULE ASSOCIATED PROTEIN tau | IQBAL KHALID (US) | 2004-01-29 | — | — | WO | disclosed |
| CN-1098124-C | Oxidation catalyst system and process for oxidation with the same | DAICEL CHEM (JP) | 2003-01-08 | — | — | CN | disclosed |
| CN-1185757-A | Oxidation catalyst system and oxidation process using the same | DAICEL CHEM (JP) | 1998-06-24 | — | — | CN | disclosed |