Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 11/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234347 | 0.86 | ROCK2 (0.49) | DRD3DRD2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31217175 | 0.83 | DRD2 (0.50) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL6242596 | 0.79 | PANK3 (0.46) | KDM4EALDH1A1L3MBTL1PROKR1 | |
| SCHEMBL2224211 | 0.74 | MAP4K4 (0.50) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29462081 | 0.74 | RET (0.48) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL12683464 | 0.73 | GPR119 (0.46) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6259732 | 0.73 | GPR119 (0.50) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14349592 | 0.72 | EGLN2 (0.53) | DRD2DRD4KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14844043 | 0.71 | SMO (0.56) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3048925 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |