Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232499 | 0.81 | MAOB (0.42) | LTB4RLTB4R2RAB9A | |
| SCHEMBL14611120 | 0.78 | TSHR (0.61) | LTB4RLTB4R2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6239905 | 0.78 | KMT2A (0.52) | LTB4RLTB4R2SMN1; SMN2PIK3CGNPC1 | |
| SCHEMBL16964474 | 0.74 | TAS1R3 (0.43) | HPGDHTTPDE4DMEN1KMT2A | |
| SCHEMBL16964035 | 0.73 | TAS1R3 (0.43) | SMN1; SMN2NPC1RAB9AHPGDHTT | |
| SCHEMBL16963959 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2RAB9AHPGDHTTMEN1 | |
| SCHEMBL8807187 | 0.70 | GAA (0.55) | SMN1; SMN2PIK3CGHTTMEN1KMT2A | |
| SCHEMBL290350 | 0.70 | ALDH1A1 (0.43) | HTTPDE4DMEN1KMT2AKDM4E | |
| SCHEMBL6234745 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2NPC1RAB9AHPGDHTT | |
| SCHEMBL6239908 | 0.69 | SMN1; SMN2 (0.53) | SMN1; SMN2PIK3CGNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |