Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16964474 | 0.77 | TAS1R3 (0.43) | ALDH1A1KMT2AMEN1PDE4APDE4B | |
| SCHEMBL16963959 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL16964035 | 0.76 | TAS1R3 (0.43) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL16335291 | 0.71 | CYP3A4 (0.54) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL3137049 | 0.70 | THRA (0.56) | ALDH1A1SCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL7774569 | 0.69 | PTGS2 (0.47) | ALDH1A1KMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL7376402 | 0.68 | TUBB4A (0.51) | ALDH1A1SCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL1436447 | 0.67 | TUBB4A (0.50) | ALDH1A1SCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL6204961 | 0.67 | CES2 (0.42) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL4819729 | 0.67 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427057-A1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | Sloan-Kettering Institute for Cancer Research (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129049-A1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-11-11 | — | — | WO | disclosed |