Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030150 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ALMNAITGB3 | |
| SCHEMBL2335798 | 0.87 | TSHR (0.46) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6412590 | 0.85 | MEN1 (0.48) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17022780 | 0.85 | TSHR (0.43) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17030209 | 0.84 | TSHR (0.42) | TSHRSMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL28182299 | 0.83 | MEN1 (0.46) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| Succinic Acid SCHEMBL27911601 | 0.83 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ALMNA | |
| Succinic Acid SCHEMBL28041968 | 0.83 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ALMNA | |
| SCHEMBL16353829 | 0.80 | CA12 (0.40) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL29046519 | 0.79 | TSHR (0.34) | TSHRMAPK1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12569427-B2 | Makeup application method | KAO CORPORATION (JP) | 2026-03-10 | — | — | US | disclosed |
| US-20230172836-A1 | MAKEUP APPLICATION METHOD | KAO CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| EP-4129417-A1 | MAKEUP APPLICATION METHOD | Kao Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |
| US-11497290-B2 | Method for producing coating film on skin by electrostatic spraying | KAO CORPORATION (JP) | 2022-11-15 | — | — | US | disclosed |
| US-11229583-B2 | Multilayer nanofiber sheet and adhesion method for same | KAO CORPORATION (JP) | 2022-01-25 | — | — | US | disclosed |
| CN-112829419-A | Multilayer nanofiber sheet and method of attaching the same | 花王株式会社 | 2021-05-25 | — | — | CN | disclosed |
| EP-3549758-B1 | MULTILAYER NANOFIBER SHEET AND ADHESION METHOD FOR SAME | KAO CORP (JP) | 2021-03-17 | — | — | EP | disclosed |
| EP-3366270-B1 | METHOD FOR PRODUCING COATING FILM | KAO CORP (JP) | 2021-02-17 | — | — | EP | disclosed |
| EP-3549758-A1 | MULTILAYER NANOFIBER SHEET AND ADHESION METHOD FOR SAME | Kao Corporation (JP) | 2019-10-09 | — | — | EP | disclosed |
| US-20190282460-A1 | MULTILAYER NANOFIBER SHEET AND ADHESION METHOD FOR SAME | KAO CORPORATION (JP) | 2019-09-19 | — | — | US | disclosed |
| US-20190053602-A1 | METHOD FOR PRODUCING COATING FILM | KAO CORPORATION (JP) | 2019-02-21 | — | — | US | disclosed |
| EP-3366270-A1 | METHOD FOR PRODUCING COATING FILM | Kao Corporation (JP) | 2018-08-29 | — | — | EP | disclosed |
| EP-1174124-B1 | PREPARATIONS FOR THE PERCUTANOUS ADMINISTRATION OF HYDROPHILIC AGENTS | KAO CORP (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6827944-B2 | Water soluble active material and polymer mixture | KAO CORPORATION (JP) | 2004-12-07 | — | — | US | disclosed |
| EP-1174124-A9 | PERCUTANEOUS ADMINISTRATION PREPARATIONS | Kao Corporation (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-1174124-A1 | PERCUTANEOUS ADMINISTRATION PREPARATIONS | Kao Corporation (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-6187955-B1 | A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS | KAO CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| US-5723133-A | GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING | KAO CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172836-A1 | MAKEUP APPLICATION METHOD | CUTA, PNN, PFN1 | TSHR 4676/4885MAPK1 1733/4885SMN1; SMN2 871/4885 |
| US-12569427-B2 | Makeup application method | LMNB1, LMNB2, PFN1 | TSHR 3911/4885MAPK1 3121/4885SMN1; SMN2 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.