Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MECP2 | P51608 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625053 | 0.89 | MEN1 (0.58) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL624171 | 0.87 | HDAC6 (0.64) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL623869 | 0.82 | NPC1 (0.59) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL625245 | 0.78 | MEN1 (0.58) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL623924 | 0.75 | ABL1 (0.56) | KDRMAPTHTTABL1EGFR | |
| SCHEMBL627181 | 0.74 | ROCK2 (0.54) | MAPK1NPC1RAB9A | |
| SCHEMBL10083553 | 0.74 | KDM4E (0.51) | MEN1KMT2ASMN1; SMN2HTTABL1 | |
| SCHEMBL9390447 | 0.74 | MEN1 (0.77) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28877702 | 0.73 | HDAC1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2HDAC6 | |
| SCHEMBL29973589 | 0.73 | HDAC1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |