Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MECP2 | P51608 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624269 | 0.89 | HTT (0.47) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL627332 | 0.83 | MAPT (0.49) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL625053 | 0.82 | MEN1 (0.58) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL624171 | 0.82 | HDAC6 (0.64) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL10083535 | 0.80 | DDX3X (0.49) | MEN1KMT2AMAPTHDAC3HDAC1 | |
| SCHEMBL6109149 | 0.79 | MCHR1 (0.64) | MEN1KMT2APOLB | |
| SCHEMBL625028 | 0.79 | DYRK1A (0.52) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL5815668 | 0.78 | MAPT (0.44) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL623943 | 0.78 | MEN1 (0.51) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL624218 | 0.78 | KCNMA1 (0.53) | MEN1KMT2APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |