Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MECP2 | P51608 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624171 | 0.90 | HDAC6 (0.64) | MEN1KMT2AMAPTSMN1; SMN2TRPV1 | |
| SCHEMBL623623 | 0.89 | KDR (0.53) | MEN1KMT2AMAPTSMN1; SMN2TRPV1 | |
| SCHEMBL623869 | 0.86 | NPC1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2HDAC6 | |
| SCHEMBL625245 | 0.82 | MEN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2TRPV1 | |
| SCHEMBL625381 | 0.76 | ADORA3 (0.62) | MEN1KMT2AMAPTSMN1; SMN2ABL1 | |
| SCHEMBL29973589 | 0.75 | HDAC1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2HDAC6 | |
| SCHEMBL28877702 | 0.75 | HDAC1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2HDAC6 | |
| SCHEMBL10083551 | 0.75 | PAX8 (0.52) | MEN1KMT2ASMN1; SMN2ABL1EGFR | |
| SCHEMBL8623427 | 0.74 | EPHX2 (0.59) | MEN1KMT2AMAPTSMN1; SMN2ABL1 | |
| SCHEMBL16151772 | 0.71 | SMN1; SMN2 (0.69) | KMT2ASMN1; SMN2HDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |