Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | BCR | P11274 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623623 | 0.75 | KDR (0.53) | ABL1SRCEGFRMAPTBCR | |
| SCHEMBL4921357 | 0.75 | MAPT (0.82) | MAPTKDRFGFR3DNMT3BMAPK1 | |
| SCHEMBL4118606 | 0.74 | MAPT (0.76) | ABL1MAPTBCRKDRFGFR3 | |
| SCHEMBL624357 | 0.73 | RAB9A (0.51) | MAPTCHEK1CDK7 | |
| SCHEMBL4123352 | 0.73 | MAPT (0.82) | MAPTKDRFGFR3DNMT3BCNR1 | |
| SCHEMBL623932 | 0.73 | RAB9A (0.59) | MAPTALDH1A1HTT | |
| SCHEMBL6258131 | 0.72 | ABL1 (1.00) | ABL1SRCEGFRBCRPDGFRA | |
| SCHEMBL4922831 | 0.71 | MAPT (0.79) | MAPTKDRFGFR3DNMT3BCNR1 | |
| SCHEMBL4912509 | 0.71 | MAPT (1.00) | MAPTCNR1 | |
| SCHEMBL627181 | 0.71 | ROCK2 (0.54) | ROCK2MAPK1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |