Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | UBE2I | P63279 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105362 | 0.88 | NCF1 (0.56) | USP2NCF1MAPTKDM4EALDH1A1 | |
| SCHEMBL6087670 | 0.88 | NCF1 (0.53) | USP2NCF1MAPTKDM4EALDH1A1 | |
| SCHEMBL6231576 | 0.87 | NCF1 (0.46) | SLC2A1USP2NCF1MAPTKDM4E | |
| SCHEMBL31620790 | 0.81 | NPSR1 (0.61) | USP2NCF1MAPTKDM4EALDH1A1 | |
| SCHEMBL23925278 | 0.80 | ALDH1A1 (0.51) | USP2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL581984 | 0.73 | HPGD (0.53) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL16928098 | 0.72 | P2RX7 (0.49) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL12614452 | 0.71 | P2RX7 (0.46) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL6100736 | 0.71 | EPHB4 (0.57) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL416225 | 0.70 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430030-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | disclosed |