Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10177473 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL178769 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL1342671 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL8544845 | 0.75 | KMT2A (0.46) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL28241182 | 0.75 | ESR1 (0.43) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL10031632 | 0.75 | ESR1 (0.43) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL2767938 | 0.75 | THRB (0.50) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL14194446 | 0.75 | KMT2A (0.46) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL8544848 | 0.75 | KMT2A (0.46) | ALDH1A1MAPTMAPK1RAB9ALMNA | |
| SCHEMBL1342675 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370760-B2 | Dithioester compound | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-06-28 | — | — | US | claimed |
| US-11214546-B2 | Dithioester compound | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-01-04 | — | — | US | claimed |
| CN-109971004-A | Perfluorinated sulfonic acid ion exchange membrane and preparation method and application thereof | 大连融科储能技术发展有限公司 | 2019-07-05 | — | — | CN | claimed |
| US-6288195-B1 | CONDENSATION POLYMERIZATION OF CYCLIC AND LINEAR ENDCAPPED POLYSILOXANES; HEATING TO DEACTIVATE CATALYST | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-09-11 | — | — | US | claimed |
| EP-0477646-B1 | Substituted 5-alkoxy-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1995-03-01 | — | — | EP | claimed |
| EP-0283876-B1 | Substituted triazolinones | BAYER AG (DE) | 1994-07-20 | — | — | EP | claimed |
| EP-0294666-B1 | Substituted triazolinones | BAYER AG (DE) | 1994-02-16 | — | — | EP | claimed |
| EP-0431390-B1 | Substituted triazolinones | BAYER AG (DE) | 1994-01-12 | — | — | EP | claimed |
| US-5276008-A | Herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| EP-0332991-B1 | Substituted triazoles | BAYER AG (DE) | 1993-11-10 | — | — | EP | claimed |
| EP-0298371-B1 | SUBSTITUTED TRIAZOLINONES | BAYER AG (DE) | 1991-10-02 | — | — | EP | claimed |
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | claimed |
| EP-0431390-A1 | Substituted triazolinones | BAYER AG (DE) | 1991-06-12 | — | — | EP | claimed |
| EP-0415196-A2 | Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1991-03-06 | — | — | EP | claimed |
| EP-0412358-A1 | 3-Amino-5-aminocarbonyl-1,2,4-triazole derivatives | BAYER AG (DE) | 1991-02-13 | — | — | EP | claimed |
| EP-0399285-A1 | Process for the preparation of 3-amino-5-aminocarbonyl-1,2,4-triazole derivatives | BAYER AG (DE) | 1990-11-28 | — | — | EP | claimed |
| EP-0398096-A1 | Substituted triazolones | BAYER AG (DE) | 1990-11-22 | — | — | EP | claimed |
| EP-0332991-A1 | Substituted triazoles | BAYER AG (DE) | 1989-09-20 | — | — | EP | claimed |
| EP-0298371-A1 | Substituted triazolinones | BAYER AG (DE) | 1989-01-11 | — | — | EP | claimed |
| EP-0283876-A2 | Substituted triazolinones | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370760-B2 | Dithioester compound | SQOR, LANCL1, AKR1C4 | ALDH1A1 47/4885MAPT 4604/4885MAPK1 1782/4885 |
| US-11214546-B2 | Dithioester compound | CBR3, CBR1, GFER | ALDH1A1 142/4885MAPT 3201/4885MAPK1 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.