Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.52 |
| ▸ | CTSL | P07711 | 6/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348149 | 0.89 | CTSK (0.67) | CTSKCTSLCTSSNPC1RAB9A | |
| SCHEMBL4041529 | 0.88 | CTSK (0.47) | CTSKCTSLCTSSALDH1A1HSD17B10 | |
| SCHEMBL8348382 | 0.87 | CTSK (0.57) | CTSKCTSSNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6209147 | 0.85 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4046526 | 0.84 | CTSK (0.72) | CTSKCTSLCTSSALDH1A1HSD17B10 | |
| SCHEMBL4037045 | 0.84 | CTSK (0.72) | CTSKCTSLCTSSALDH1A1HSD17B10 | |
| SCHEMBL4041263 | 0.84 | CTSK (0.66) | CTSKCTSLCTSSALDH1A1HSD17B10 | |
| SCHEMBL6233220 | 0.83 | CHRNB2 (0.48) | CTSKSMN1; SMN2TP53HTTCHRNB2 | |
| SCHEMBL4037326 | 0.82 | CTSK (0.65) | CTSKCTSLCTSSALDH1A1HSD17B10 | |
| SCHEMBL4039935 | 0.82 | CTSK (0.65) | CTSKCTSLCTSSALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |