Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348382 | 0.89 | CTSK (0.57) | CHRNB2CHRNA7CHRNA4GAACTSK | |
| SCHEMBL4050081 | 0.89 | CTSK (0.42) | CHRNB2CHRNA7CHRNA4GAACTSK | |
| SCHEMBL4044197 | 0.85 | CTSK (0.63) | CHRNB2CHRNA7CHRNA4CTSKLMNA | |
| SCHEMBL4042794 | 0.84 | CTSK (0.57) | CTSK | |
| SCHEMBL8348149 | 0.83 | CTSK (0.67) | CTSKCAPN1SMN1; SMN2MAPK1 | |
| SCHEMBL6237263 | 0.83 | CTSK (0.52) | CHRNB2CHRNA7CHRNA4CTSKSMN1; SMN2 | |
| SCHEMBL4047037 | 0.82 | CTSK (0.56) | CTSKLMNA | |
| SCHEMBL4041333 | 0.81 | CTSK (0.69) | GAACTSKLMNASMN1; SMN2HTT | |
| SCHEMBL4041842 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4GAACTSK | |
| SCHEMBL4040431 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4GAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |