Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348149 | 0.92 | CTSK (0.67) | CTSKCTSSSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL6233220 | 0.89 | CHRNB2 (0.48) | CTSKCHRNB2CHRNA7CHRNA4GAA | |
| SCHEMBL6237263 | 0.87 | CTSK (0.52) | CTSKCHRNB2CHRNA7CHRNA4CTSS | |
| SCHEMBL13909120 | 0.85 | CTSK (0.57) | CTSKCTSS | |
| SCHEMBL4043042 | 0.82 | CTSK (0.68) | CTSKCTSSPREPFAPALDH1A1 | |
| SCHEMBL4215661 | 0.81 | CTSK (0.82) | CTSKCTSSPREPFAPLMNA | |
| SCHEMBL5941468 | 0.81 | CTSK (0.82) | CTSKCTSSPREPFAPLMNA | |
| SCHEMBL4041237 | 0.81 | CTSK (0.82) | CTSKCTSSPREPFAPLMNA | |
| SCHEMBL4215663 | 0.81 | CTSK (0.82) | CTSKCTSSPREPFAPLMNA | |
| SCHEMBL8349685 | 0.81 | CTSK (0.60) | CTSKCTSSPREPFAPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |