Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 14/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609810 | 0.83 | DGAT1 (0.45) | DGAT1SOAT1KCNH2 | |
| SCHEMBL6284522 | 0.80 | DGAT1 (0.52) | DGAT1SOAT1KCNH2KIF11NOTUM | |
| SCHEMBL11166567 | 0.80 | KIF11 (0.45) | DGAT1SOAT1KCNH2KIF11NOTUM | |
| SCHEMBL11161344 | 0.77 | ERCC1 (0.53) | DGAT1SOAT1KCNH2NOTUM | |
| SCHEMBL28025803 | 0.76 | NOTUM (0.46) | DGAT1SOAT1KCNH2KIF11NOTUM | |
| SCHEMBL611156 | 0.75 | PDE3B (0.52) | DGAT1SOAT1KCNH2KIF11NOTUM | |
| SCHEMBL197238 | 0.75 | KIF11 (0.78) | KIF11 | |
| SCHEMBL29914837 | 0.75 | KIF11 (0.78) | KIF11 | |
| SCHEMBL13410633 | 0.75 | KIF11 (0.78) | KIF11 | |
| SCHEMBL11536096 | 0.74 | ALDH1A1 (0.48) | DGAT1SOAT1KCNH2KIF11BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |