Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237876 | 0.83 | DGAT1 (0.58) | DGAT1SOAT1KCNH2 | |
| SCHEMBL11536096 | 0.81 | ALDH1A1 (0.48) | DGAT1SOAT1KCNH2ALDH1A1GAA | |
| SCHEMBL11533580 | 0.80 | MEN1 (0.48) | DGAT1SOAT1KCNH2GAAMEN1 | |
| SCHEMBL2635488 | 0.74 | ALDH1A1 (0.48) | DGAT1SOAT1KCNH2ALDH1A1GAA | |
| SCHEMBL11537063 | 0.73 | TRPM8 (0.37) | DGAT1SOAT1KCNH2ALDH1A1GAA | |
| SCHEMBL24880084 | 0.73 | ALDH1A1 (0.41) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL6284522 | 0.72 | DGAT1 (0.52) | DGAT1SOAT1KCNH2MEN1KMT2A | |
| SCHEMBL2704950 | 0.71 | GFER (0.37) | ALDH1A1HSD17B10DAOCES2CES1 | |
| SCHEMBL11540051 | 0.71 | ALDH1A1 (0.40) | DGAT1SOAT1KCNH2ALDH1A1GAA | |
| SCHEMBL21324857 | 0.70 | NPC1 (0.43) | ALDH1A1MEN1KMT2APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-04-24 | — | — | US | claimed |
| CN-115052875-B | 4- (4, 5-Dihydroisoxazol-3-yl) thiazol-2-yl) piperidine-thioimine or sulphoxide-imine derivatives and related compounds as fungicides for crop protection | PI工业有限公司 | 2024-07-12 | — | — | CN | claimed |
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | claimed |
| CN-115052875-A | 4- (4- (4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidinethimine or sulfoximine derivatives as fungicides for crop protection and related compounds | PI工业有限公司 | 2022-09-13 | — | — | CN | claimed |
| WO-2018193387-A1 | HETEROCYCLIC COMPOUNDS WITH MICROBIOCIDAL PROPERTIES | PI INDUSTRIES LTD. (IN) | 2018-10-25 | — | — | WO | claimed |
| US-4249009-A | Processes for preparing 2-chloro-5-trifluoromethylpyridine | REILLY TAR & CHEMICAL CORP. (US) | 1981-02-03 | — | — | US | claimed |
| US-4230864-A | Process for making 5-trifluoromethyl pyridone | REILLY TAR & CHEMICAL CORP. (US) | 1980-10-28 | — | — | US | claimed |
| JP-55124763-A | — | — | None | — | — | JP | disclosed |
| JP-56090059-A | — | — | None | — | — | JP | disclosed |
| JP-62026270-A | — | — | None | — | — | JP | disclosed |
| WO-2026098657-A1 | HETEROCYCLIC COMPOUND AS MEK INHIBITOR | 先声再明医药股份有限公司 | 2026-05-15 | — | — | WO | disclosed |
| CN-122036680-A | Anti-fibrotic pyridones | 英特穆恩公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-4249009-A | Processes for preparing 2-chloro-5-trifluoromethylpyridine | REILLY TAR & CHEMICAL CORP. (US) | 1981-02-03 | — | — | US | disclosed |
| US-4249009-A | Processes for preparing 2-chloro-5-trifluoromethylpyridine | REILLY TAR & CHEMICAL CORP. (US) | 1981-02-03 | — | — | US | disclosed |
| US-4244953-A | Substituted 6-phenyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4230864-A | Process for making 5-trifluoromethyl pyridone | REILLY TAR & CHEMICAL CORP. (US) | 1980-10-28 | — | — | US | disclosed |
| JP-S55124763-A | 5-TRIFLUOROMETHYL-2-PYRIDONE DERIVATIVE | ISHIHARA SANGYO KAISHA LTD | 1980-09-26 | — | — | JP | disclosed |
| US-4131677-A | Anti-inflammatory oxazolo [5,4-b]pyridines | MERCK & CO., INC. (US) | 1978-12-26 | — | — | US | disclosed |
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | AHR, ARNT, AIPL1 | DGAT1 1616/4885SOAT1 1477/4885KCNH2 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.