Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909466 | 0.79 | NR3C2 (0.36) | HTTLMNAPSIP1ALDH1A1NPSR1 | |
| SCHEMBL16710174 | 0.73 | CA1 (0.46) | CA1CA2CA9SOS1CA5A | |
| SCHEMBL9541482 | 0.72 | PPARG (0.39) | NPSR1PPARG | |
| SCHEMBL5286690 | 0.71 | TAAR1 (0.40) | ALDH1A1NPSR1PPARG | |
| SCHEMBL9451426 | 0.70 | CA2 (0.46) | CA1CA2CA9SOS1ALDH1A1 | |
| SCHEMBL4909452 | 0.70 | ALDH1A1 (0.37) | CA9HTTLMNACA12ALDH1A1 | |
| Sulfuric Acid SCHEMBL3204394 | 0.70 | CA1 (0.37) | CA1CA2CA9SOS1HTT | |
| Sulfamate SCHEMBL9451431 | 0.70 | CA1 (0.41) | CA1CA2CA9SOS1ALDH1A1 | |
| SCHEMBL3081094 | 0.70 | LTA4H (0.40) | LMNANPSR1CYP2C19PPARG | |
| SCHEMBL1453725 | 0.70 | LTA4H (0.40) | NPSR1CYP2C19PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050632-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | WO | disclosed |