Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 11/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235020 | 0.79 | NOTUM (0.48) | NOTUMARKDM4E | |
| SCHEMBL21542324 | 0.77 | NOTUM (0.50) | NOTUMKDM4EALDH1A1 | |
| SCHEMBL21624776 | 0.75 | NOTUM (0.64) | NOTUMARACACB | |
| SCHEMBL21624778 | 0.75 | NOTUM (0.64) | NOTUMARACACB | |
| SCHEMBL1409422 | 0.75 | NOTUM (0.67) | NOTUMARACACB | |
| SCHEMBL6232950 | 0.75 | ALDH1A1 (0.57) | NOTUMKDM4EALDH1A1 | |
| SCHEMBL2928855 | 0.74 | HTR3E (0.55) | NOTUMARALDH1A1 | |
| SCHEMBL11453106 | 0.74 | NOTUM (0.51) | NOTUMAR | |
| SCHEMBL31193968 | 0.73 | PDE3B (0.53) | NOTUMARKDM4EPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL2276790 | 0.73 | THRB (0.56) | NOTUMARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |