Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.72 |
| ▸ | DRD3 | P35462 | 6/20 | 0.72 |
| ▸ | HTR1A | P08908 | 4/20 | 0.70 |
| ▸ | HTR7 | P34969 | 4/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264690 | 0.92 | DRD2 (0.72) | DRD2DRD3HTR1AHTR7ADRA1A | |
| SCHEMBL1491175 | 0.88 | HTR1A (0.71) | DRD2DRD3HTR1AHTR7ADRA1A | |
| SCHEMBL3162960 | 0.87 | DRD2 (0.76) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL6237142 | 0.85 | ALDH1A1 (0.65) | DRD2DRD3HTR1AHTR7ADRA1A | |
| SCHEMBL11030623 | 0.85 | HTR1A (0.73) | DRD2HTR1AHTR7 | |
| SCHEMBL14761584 | 0.84 | DRD2 (0.94) | DRD2DRD3HTR1AADRA1ADRD4 | |
| SCHEMBL19580052 | 0.83 | DRD2 (0.81) | DRD2DRD3HTR1AADRA1ADRD4 | |
| SCHEMBL9653869 | 0.83 | DRD2 (0.78) | DRD2DRD3HTR1AADRA1ADRD4 | |
| Benzene SCHEMBL10433203 | 0.83 | HTR1A (0.79) | DRD2DRD3HTR1AHTR7ADRA1A | |
| SCHEMBL3160665 | 0.83 | HTR1A (0.79) | DRD2DRD3HTR1AHTR7ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018643-A1 | METABOLITES OF 1-{3-4`4-(2-METHOXYPHENYL) PIPERAZIN-1-YL!-PROPYL}-PIPERIDINE-2, 6-DIONE FOR USE IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |