Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240374 | 0.79 | MAPT (0.46) | KMT2ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL4002538 | 0.74 | KMT2A (0.55) | KMT2ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL4009678 | 0.73 | RAB9A (0.52) | KMT2ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL4002897 | 0.71 | RAB9A (0.49) | KMT2ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL6243802 | 0.70 | KMT2A (0.47) | KMT2ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL6243775 | 0.67 | KDM4E (0.43) | KMT2ASMN1; SMN2MAPTPOLBCCNT1 | |
| SCHEMBL4005068 | 0.64 | KMT2A (0.48) | KMT2ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL3488077 | 0.61 | ALDH1A1 (0.69) | KMT2ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL4003903 | 0.61 | KDM4E (0.50) | KMT2ASMN1; SMN2MAPTPOLBDRD4 | |
| SCHEMBL4004550 | 0.61 | SMN1; SMN2 (0.54) | KMT2ASMN1; SMN2ALDH1A1CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |