Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.34 |
| ▸ | CDK9 | P50750 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240374 | 0.87 | MAPT (0.46) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6242558 | 0.84 | KDM4E (0.53) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6240789 | 0.78 | MAPT (0.48) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6239771 | 0.76 | HTR1A (0.43) | LMNASIGMAR1HTR1A | |
| SCHEMBL4003903 | 0.76 | KDM4E (0.50) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6244798 | 0.74 | CYP2D6 (0.55) | MAPTKMT2ASMN1; SMN2POLBPKM | |
| SCHEMBL6244316 | 0.74 | HTT (0.53) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6242433 | 0.69 | HTR1A (0.41) | KDM4EMAPTLMNAHTR1A | |
| SCHEMBL7146208 | 0.69 | KDM4E (0.36) | KDM4EMAPTLMNAKMT2APOLB | |
| SCHEMBL6239012 | 0.67 | KMT2A (0.43) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |