Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243775 | 0.87 | KDM4E (0.43) | MAPTPOLBPKMKDM4ELMNA | |
| SCHEMBL6239012 | 0.79 | KMT2A (0.43) | MAPTRAB9APOLBTSHRALDH1A1 | |
| SCHEMBL6240789 | 0.78 | MAPT (0.48) | MAPTTSHRALDH1A1KDM4ELMNA | |
| SCHEMBL4009678 | 0.78 | RAB9A (0.52) | MAPTRAB9APOLBTSHRALDH1A1 | |
| SCHEMBL6244316 | 0.77 | HTT (0.53) | MAPTPOLBALDH1A1KDM4ELMNA | |
| SCHEMBL6242558 | 0.77 | KDM4E (0.53) | MAPTRAB9APOLBALDH1A1KDM4E | |
| SCHEMBL4002897 | 0.76 | RAB9A (0.49) | MAPTRAB9APOLBTSHRALDH1A1 | |
| SCHEMBL6244798 | 0.74 | CYP2D6 (0.55) | MAPTPOLBALDH1A1PKMKMT2A | |
| SCHEMBL4002538 | 0.73 | KMT2A (0.55) | MAPTRAB9APOLBTSHRALDH1A1 | |
| SCHEMBL6239771 | 0.72 | HTR1A (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |