Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 15/20 | 0.46 |
| ▸ | CA1 | P00915 | 15/20 | 0.46 |
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA7 | P43166 | 13/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 11/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA6 | P23280 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411266 | 0.85 | PTGS2 (0.43) | PTGS1PTGS2ALDH1A1HSD17B10ALOX5AP | |
| SCHEMBL15925025 | 0.79 | CA12 (0.42) | CA12CA1CA2CA7CA13 | |
| SCHEMBL8534063 | 0.79 | CA1 (0.42) | CA12CA1CA2CA7CA13 | |
| SCHEMBL6239020 | 0.78 | BCAT2 (0.49) | CA12CA1CA2CA7CA13 | |
| SCHEMBL7554444 | 0.77 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL27979836 | 0.77 | CA12 (0.47) | CA12CA1CA2CA7CA13 | |
| SCHEMBL6564249 | 0.77 | ALDH1A1 (0.54) | CA12CA1CA2CA7CA13 | |
| SCHEMBL28782417 | 0.76 | PGR (0.34) | PTGS1PTGS2ALOX5APFEN1 | |
| SCHEMBL28164099 | 0.76 | CA12 (0.42) | CA12CA1CA2CA7CA13 | |
| SCHEMBL28511724 | 0.75 | ALOX5AP (0.53) | ALDH1A1HSD17B10ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539686-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004024679-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-25 | — | — | WO | claimed |
| EP-1539686-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024679-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-25 | — | — | WO | disclosed |