Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.52 |
| ▸ | ITGAL | P20701 | 3/20 | 0.52 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980936 | 0.88 | CYP3A4 (0.51) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6240992 | 0.86 | ITGB2 (0.46) | ITGB2ICAM1ITGALCYP3A4ALDH1A1 | |
| SCHEMBL5907039 | 0.85 | AGTR2 (0.57) | ITGB2ICAM1ITGALGGT1CA1 | |
| SCHEMBL3599440 | 0.85 | AGTR2 (0.57) | ITGB2ICAM1ITGALGGT1CA1 | |
| SCHEMBL2974165 | 0.80 | ITGB2 (0.54) | ITGB2ICAM1ITGALGGT1CA1 | |
| SCHEMBL28047866 | 0.79 | GGT1 (0.51) | ITGB2ICAM1ITGALGGT1CA1 | |
| SCHEMBL28047867 | 0.79 | GGT1 (0.51) | ITGB2ICAM1ITGALGGT1CA1 | |
| SCHEMBL1667212 | 0.78 | ALDH1A1 (0.54) | ITGB2ICAM1ITGALCYP3A4ALDH1A1 | |
| SCHEMBL6234672 | 0.77 | POLB (0.61) | ALDH1A1HIF1A | |
| SCHEMBL2978710 | 0.77 | CYP3A4 (0.49) | ITGB2ICAM1ITGALGGT1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | claimed |
| EP-0629606-B1 | AMINO ACID DERIVATIVE AND ANTI-ACTIVE-OXYGEN AGENT | AJINOMOTO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5594012-A | OXIDATION RESISTANCE | AJINOMOTO CO., INC. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0629606-A1 | AMINO ACID DERIVATIVE AND ANTI-ACTIVE-OXYGEN AGENT | Ajinomoto Co., Inc. (JP) | 1994-12-21 | — | — | EP | disclosed |