Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.54 |
| ▸ | ITGAL | P20701 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599440 | 0.87 | AGTR2 (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C19ITGB2 | |
| SCHEMBL5907039 | 0.87 | AGTR2 (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C19ITGB2 | |
| SCHEMBL2980936 | 0.85 | CYP3A4 (0.51) | ALDH1A1CYP1A2CYP3A4CYP2C19ITGB2 | |
| SCHEMBL2974165 | 0.84 | ITGB2 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19ITGB2 | |
| SCHEMBL5869520 | 0.83 | AGTR2 (0.61) | CYP3A4ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL8250332 | 0.83 | AGTR2 (0.61) | CYP3A4ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL9554563 | 0.81 | GGT1 (0.55) | ALDH1A1CYP1A2CYP3A4CYP2C19ITGB2 | |
| SCHEMBL9829801 | 0.80 | AGTR2 (0.60) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL8249066 | 0.79 | REN (0.53) | — | |
| SCHEMBL5870452 | 0.79 | REN (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | claimed |
| CN-102711802-B | Peptidic GLP-2 agonists | 辉凌公司 | 2017-03-22 | — | — | CN | disclosed |
| EP-2490709-B1 | PEPTIDIC GLP-2 AGONISTS | FERRING BV (NL) | 2014-11-26 | — | — | EP | disclosed |
| US-8580918-B2 | Peptidic GLP-2 agonists | FERRING B.V. (NL) | 2013-11-12 | — | — | US | disclosed |
| CN-102711802-A | Peptidic GLP-2 agonists | FERRING BV | 2012-10-03 | — | — | CN | disclosed |
| US-20120231999-A1 | PEPTIDIC GLP-2 AGONISTS | FERRING B.V. (NL) | 2012-09-13 | — | — | US | disclosed |
| CN-101531637-B | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GUANGZHOU INST OF BIOMEDICINE AND HEALTH | 2011-07-13 | — | — | CN | disclosed |
| EP-2314616-A1 | Peptidic GLP-2 agonists | Ferring B.V. (NL) | 2011-04-27 | — | — | EP | disclosed |
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231999-A1 | PEPTIDIC GLP-2 AGONISTS | GLP1R, GIPR, IAPP | ALDH1A1 4333/4885CYP1A2 2441/4885CYP3A4 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.