Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | UBE2N | P61088 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987603 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL1987380 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL20911243 | 0.82 | ALDH1A1 (0.76) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL12599534 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL3668189 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL14373932 | 0.77 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL276275 | 0.77 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL3587397 | 0.76 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL10532167 | 0.76 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKMT2ALCK | |
| SCHEMBL304332 | 0.74 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AKMT2ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137239-A1 | Thiazole derivatives | AVON PRODUCTS, INC. | 2005-06-23 | — | — | US | disclosed |
| EP-1543824-A2 | Thiazole derivatives to counter advanced glycation | Avon Products, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137239-A1 | Thiazole derivatives | TYR, AGER, AOX1 | ALDH1A1 82/4885NPC1 3747/4885RAB9A 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.